Clinical Trial Site Selection: Best Practices for UK Studies

Clinical trial site selection concept showing one protocol shape tested against three candidate site apertures, with only the matching site accepting its silhouette

Best practice in clinical trial site selection is to choose each site against evidence it has already produced, rather than the estimate on its feasibility form. This guide covers what the April 2026 UK rules put on the decision, the nine criteria that predict delivery, how to test a site’s real access to its population, and the measures that show whether the choice was right.

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✓ Written for first-in-human & Phase 1 sites

✓ Inspection-ready checklists & templates

✓ Aligned to MHRA, FDA & EU Annex 11