Patient Recruitment in Clinical Trials: Strategies for UK Studies
Patient recruitment converts a defined eligible population into consented, randomised participants. This guide covers the five-step recruitment pipeline and who owns each step, where UK studies lose recruitment time against the national indicators, what the April 2026 regulations require before a site consents anyone, and five strategies that hold up in practice.
What Is ORR in Clinical Trials? Objective Response Rate Explained
Objective response rate (ORR) is the proportion of participants whose tumour shrank by a predefined amount. It is the sum of complete responses and partial responses, divided by the number of evaluable participants. Stable disease is excluded. ORR answers one question, at one point in time: did the treatment produce measurable tumour shrinkage in this […]
How Long Do Clinical Trials Take?
Clinical trials take 10 to 15 years or more to complete all three phases before licensing, and the years accumulate between the regulators’ clocks rather than inside them. This guide covers what sets each phase’s length, the UK approval clocks in force since 28 April 2026, where a study loses time after approval, and how long licensing takes.
What are the 4 Phases of Clinical Trials?
The clinical trial research is divided into four distinct phases, each serving a specific purpose in the pursuit of safe and reliable medicines. These phases constitute a structured journey, guiding investigational products from their initial introduction to thorough evaluation and eventual widespread usage. All of this is effectively planned and executed with the help of […]
What Are Decentralised Clinical Trials? Methods, Risks and UK Rules
Decentralised clinical trials run trial activity at locations other than the investigator site. This guide covers the seven methods that decentralise a study, the artefacts where delivery breaks down, the five sponsor expectations the HRA and MHRA set out, and what the UK rules have required since 28 April 2026.
What is EDC in Clinical Trials?
Electronic Data Capture (EDC) is software used in clinical trials to collect and manage data digitally, replacing traditional paper-based methods. It utilizes electronic case report forms (eCRFs), which are web-based questionnaires designed to collect data about study participants. EDC enhances the quality, speed, and accuracy of clinical trials in real-time, ensuring ultimate precision and efficiency […]
