What is a Commercial Research Delivery Centre (CRDC) and How Does Multi-Site Research Oversight Work?
A Commercial Research Delivery Centre (CRDC) is an NIHR-designated centre that expands delivery of commercial clinical research through a hub-and-spoke model, where a lead NHS organisation coordinates partner sites. Twenty-one CRDCs opened across the UK in April 2025. Each runs studies under MHRA and ICH-GCP E6(R3) requirements, and the hub holds oversight of every spoke. […]
Study Set-Up Challenges: An Operational Problem Taxonomy
Study set-up challenges fall into six operational classes, and each one hides the same failure: a dependency the study record does not hold. This guide sets out the six classes, the artefact that settles each, where published start-up data shows the time actually goes, and what a study record must hold before the first participant.
